top of page

2024

87. Ang, H.; Miao, Y.; Ravelli, D.; & Wu, J. (2024). "Pyridine N-oxides as hydrogen atom transfer reagents for site-selective photoinduced C(sp3)–H functionalization" Nature Synthesis, 2024. [PDF Download] DOI: https://doi.org/10.1038/s44160-024-00528-2

86. Lei, Z.; & Wu, J. (2024). "Terminal-selective C(sp3)–H borylation of unbranched alkanes enabled by intermolecular radical sampling and LMCT photocatalysis" National Science Review, 2024. [PDF Download] DOI: https://doi.org/10.1093/nsr/nwae105

85. Song, L.; Ang, H. T.; Senthilperumal, J.; Kanusu, U. R.; Venugopal, S.; Rangarajan, N.; Krishnamoorthy, S.; Dubbaka, S., R.; O'Neill. P. & Wu, J. (2024). "1,2,3-Triazole Synthesis: Development of Safe and Effective Batch and Continuous Manufacturing Processes" Org. Process Res. Dev., 2024. [PDF Download] DOI: https://doi-org.libproxy1.nus.edu.sg/10.1021/acs.oprd.4c00020

84 TOC.png

84. Liu, C.; Song, L.; Liu, Q.; Chen, W.; Xu, J.; Wang, M.; Zhang, Y.; Tan, T., W.; Lei, Z.; Cheng, L.; Khan SA.; & Wu, J. (2024). "High-Speed Circulation Flow Platform Facilitating Practical Large-Scale Heterogeneous Photocatalysis." Org. Process Res. Dev., 2024. [PDF Download] DOI: https://doi-org.libproxy1.nus.edu.sg/10.1021/acs.oprd.

83. Zhang, X.; Li, S.; Qiu, F.; Ang, H. T.; Wu, J. & Jia, P. (2024) "Photocatalyzed Minisci-type reactions for late-stage
functionalization of pharmaceutically relevant compounds" Green Chem., 2024. [PDF Download] DOI: https://doi.org/10.1039/D3GC05089K

82. Wang, Q.; Yin, R.; Wang, Z.; Zhang, Y.; Wu, J. (2023) "Application of stop‑flow micro‑tubing reactor system in organic reaction development" Journal of Flow Chemistry, 2023. [PDF Download] DOI: https://doi.org/10.1007/s41981-023-00302-z

2023

81. Qi, J.; Wang, X.; Wang, G.; Dubbaka, S.; O`Neil, P.; Ang, H.; Wu, J. (2023) "Sustainable electrocatalytic oxidation of N-alkylamides to acyclic imides using H2O" Green Chemistry, 2024. [PDF Download] DOI: https://doi.org/10.1039/D3GC04010K

81 TOC.png

80. Lei, Z.; Zhang, W.; Wu, J. (2023) "Photocatalytic hydrogen atom transfer-induced Arbuzov-type α-C(sp3)-H phosphonylation of aliphatic amines" ACS Catalysis, 2023. [PDF Download] DOI: https://doi.org/10.1021/acscatal.3c04621

79. Qi, J.; Xu, J.; Ang, H. T.; Wang, B.; Gupta, N.; Dubbaka, S.; O'Neill, P.; Mao, X.; Lum, Y.; Wu, J. (2023) "Electrophotochemical Synthesis Facilitated Trifluoromethylation of Arenes Using Trifluoroacetic Acid" J. Am. Chem. Soc. 2023. [PDF Download​] DOI: https://doi.org/10.1021/jacs.3c10148

TOC.tif

78. Song, L.; Wu, J. (2023) "Modular synthesis of β-amino acids from alkenes, amines, and CO2 via photoredox/copper dual catalysis" Science China Chemsitry 2023. [PDF Download​] DOI: https://doi.org/10.1007/s11426-023-1848-9

77. Hai, X.; Zheng, Y.; Yu, Q.; Guo, N.; Xi, S.; Zhao, X.; Mitchell, S.; Luo, X.; Tulus, V.; Wang, M.; Sheng, X.; Ren, L.; Long, X.; Li, J.; He, P.; Lin, H.; Cui, Y.; Peng, X.; Shi, J.; Wu, J.; Zhang, C.; Zou, R.; Guillén-Gosálbez, G.; Pérez-Ramírez, J.; Koh, M. J.; Zhu, Y.; Li, J & Lu, J. (2023) "Geminal-atom Catalysis for Cross-coupling" Nature 2023. [PDF Download​] DOI: https://doi.org/10.1038/s41586-023-06529-z

76. Zhang, Z., Wang, C., Li, L., Piper, J. L., Peng, Z., Ma, J., Zhang, F. & Wu, J. (2023) "Programmable Synthesis of Difluorinated Hydrocarbons from Alkenes through a Photocatalytic Linchpin Strategy" Chem. Sci. 2023, Accepted.

76 TOC.png

75. Zhang, W., Liu, T., Ang, H. T., Luo, P., Lei, Z., Luo, X., Koh, M. J. & Wu, J. (2023) "Modular and Practical 1,2-Aryl(alkenyl) Heteroatom Functionalization of Alkenes through Iron/Photoredox Dual Catalysis" Angew. Chem. Int. Ed. 2023, e202310978. [PDF Download​] DOI: https://doi.org/10.1002/anie.202310978

74. Xu, J., Xu, W., Zhang, X., Wu, J., Zhang, P., Song, L., & Liu, X. (2023) "Divergent Synthesis of Quinolones through Radical C–H Functionalization/Cyclization" Advanced Synthesis & Catalysis. [PDF Download​] DOI: https://doi.org/10.1002/adsc.202300426

73. Yang, H.#, Xu, J.#, Cao, H., Wu, J.* & Zhao, Dan.*. (2023) "Recovery of Homogeneous Photocatalysts by Covalent Organic Framework Membranes" Nature Communications. 14, 2726. [PDF Download] DOI: https://doi.org/10.1038/s41467-023-38424-6

  • This paper was featured by X-MOL, 

 

72. Wang, G., Ang, H., T., & Wu, J.*. (2023). "Multi-Step Automated Synthesis of Pharmaceuticals" Trends in Chemistry. Accepted. [PDF Download] DOI: https://doi.org/10.1016/j.trechm.2023.03.008

71. Zhu, K., Ma, Y., Wu, Z., Wu, J.* & Lu, Y.*. (2023). "Energy-Transfer-Enabled Regioconvergent Alkylation of Azlactones via Photocatalytic Radical–Radical Coupling" ACS Catalysis, 13, 4894–4902. [PDF Download] DOI: https://doi.org/10.1021/acscatal.2c05698

70. Kong, D.#, Zhang, M.#, Zhang, Y., Yu, Z., Cao, H.*, & Wu, J.*. (2023). "Photocatalyzed Regioselective Hydrosilylation for the Divergent Synthesis of Geminal and Vicinal Borosilanes." Nature Communications. 14, 2525. [PDF Download] DOI: https://doi.org/10.1038/s41467-023-38224-y

  • This paper was featured by X-MOL, 

69. Lei, Z., Ang, H., T., & Wu, J.* (2023). "Advanced In-line Purification Technologies in Multistep Continuous Flow Pharmaceutical Synthesis." Organic Process Research & Development. Accepted. [PDF Download] DOI: https://doi.org/10.1021/acs.oprd.2c00374

 

 

68. Lim, Y.-J., Tang, G., Ye, Z., Zhang, C.-J. Wu, J.*, & Yao, S. Q.* (2023). "A Late-Stage Aryl C-H Olefination Strategy and Its Application Towards Global Proteome Profiling of ∆8-Tetrahydrocannabinol." Chemistry - A European Journal. e202300531. [PDF Download​] DOI: https://doi.org/10.1002/chem.202300531

67. Ng, X. Q.#, Lim, C. S.#, Liaw, M. W., Quanch, T. T., Yang, B., Isoni, V., Wu, J.*, & Zhao, Y.* (2023). "Direct Access to Chiral Aliphatic Amines by Catalytic Enantioconvergent Redox-neutral Amination of Alcohols." 

Nature Synthesis. 2, 572–580. [PDF Download] DOI: https://doi.org/10.1038/s44160-023-00264-z

66. Yuan, Y.#, Zhang, M.#, Tang, X., Piper, J. L., Peng, Z. H., Ma, J. A.*, Wu, J.*, & Zhang, F. G.* (2023). "Photoinduced Defluorinative Branch-Selective Olefination of Multifluoro (Hetero) arenes." Organic Letters. 25, 883−888. [PDF Download] DOI: https://doi.org/10.1021/acs.orglett.3c00115

65. Fan, X.#, Zhang, M.#, Gao, Y., Zhou. Q., Zhang, Y., Yu, J., Xu, W., Yan, J., Liu, H., Lei, Z., Ter, Y. C., Chanmungkalakul, S., Lum, Y., Liu, X., Cui, G., & Wu, J.* (2023)."Stepwise On-demand Functionalization of Multihydrosilanes Enabled by a Hydrogen-atom-transfer Photocatalyst Based on Eosin Y." Nature Chemistry. 15, 666–676. [PDF Download​] DOI: https://doi.org/10.1038/s41557-023-01155-8

  • This paper was featured by X-MOL, 

 

64. Tang, H., Zhang, M.*, Zhang, Y., Luo, P., Ravelli, D.; Wu, J.* (2023)."Direct Synthesis of Thioesters from Feedstock Chemicals and Elemental Sulfur." Journal of the American Chemical Society. 145(10), 5846–5854. [PDF Download] DOI: https://doi.org/10.1021/jacs.2c13157

  • This paper was featured by X-MOL, 

 

 

63. Wu, Z., Wu, M., Zhu, K., Wu, J.*, Lu, Y.* (2023)."Photocatalytic Coupling of Electron-deficient Alkenes using Oxalic Acid as a Traceless Linchpin." Chem. 9(4), 978-988. [PDF Download​] DOI: https://doi.org/10.1016/j.chempr.2022.12.013

Picture1.png
Picture4.png
Picture3.png
Picture2.png
微信图片_20230327115402.jpg
fig intro 透明.png
Picture1_edited.png

2022

62. Cai, B., Toh, R. W., Ang, H., T., Wu, J.*, Panek, J. S.* (2022). "Stereo- and Regioselective Synthesis of (E,E)-Dienes: Evolution from the Transition-Metal Catalyzed Cross-Coupling to Titanium Alkoxide-Based Alkyne-Alkyne Reductive Coupling." Synlett, 33, A–W. [PDF Download​] DOI: https://doi.org/10.1055/a-1977-1006

 

61. Yu, J., Zhang, X., Wu, X., Liu, T., Zhang, Z., Wu, J.*, Zhu, C.* (2022). "Metal-free Radical Difunctionalization of Ethylene." Chem, 9, 472–482. [PDF Download] DOI: https://doi.org/10.1016/j.chempr.2022.10.020

 

 

 

 

 

 

60. Yang, X., Lim, S. H. M., Lin, J., Wu, J., Tang, H., Zhao, F., Liu, F., Sun, C., Shi, X., Kuang, Y., Toy Y. H., Du, K., Zhang, Y., Wang, X., Sun, M., Song, Z., Wang, T., Wu, J., Houk K. N.*, Huang, D.* (2022). "Oxygen Mediated Oxidative Couplings of Flavones in Alkaline Water." Nature Communications, 13, 6424. [PDF Download​] DOI: https://doi.org/10.1038/s41467-022-34123-w

59. Yang, H.#, Xi, S.#, Guo, N.#, Wang, M., Liu, L., Lyu, P., Yu, X., Li, J., Xu, H., Hai, X., Li, Z., Li, X., Sun, T., Zhao, X, Han, Y., Wu, J., Zhang, C.*, Fei, H.*, Koh, M. J.*, Lu, J.* (2022). "Catalytically Active Atomically Thin Cuprate with Periodic Cu Single Sites." National Science Review, nwac100. [PDF Download] DOI: https://doi.org/10.1093/nsr/nwac100

58. Ng, X. Q.; Kang, M. H.; Toh, R. W.; Isoni, V.*; Wu, J.*, Zhao, Y.* (2022). "A green access to supported cinchona alkaloid amide catalysts for heterogeneous enantioselective allylsilylation of aldehydes and process intensity evaluation in batch and flow." Green Synthesis and Catalysis. 272-277. [PDF Download] DOI: https://doi.org/10.1016/j.gresc.2022.07.004

 

57. Li, Q.; Dai, P.; Tang, H.; Zhang, M.*; Wu, J.* "Photomediated Reductive Coupling of Nitroarenes with Aldehydes for Amide Synthesis". Chem. Sci. 2022, 13, 9361–9365. [PDF Download] DOI: https://doi.org/10.1039/D2SC03047K.

 

 

56. Zhang, Z.; Sang, Y.; Wang, C.; Dai, P.; Xue, X.; Piper, J. L.; Peng, Z.; Ma, J.*; Zhang, F.*; Wu, J.* “Difluoromethylation of Unactivated Alkenes Using Freon-22 through Tertiary Amine-borane-triggered Halogen-atom Transfer”. J. Am. Chem. Soc. 2022, 144, 14288–14296. [PDF Download] DOI: https://doi.org/10.1021/jacs.2c05356

55. Cao, H.; Kong, D.; Yang. L.; Chanmungkalakul, S.; Liu, T.; Piper, J. L.; Peng, Z.; Gao, L.; Liu, X.; Hong, X.*, Wu, J.* “Bronsted Acid-Enhanced Direct Hydrogen Atom Transfer Photocatalysis to Enable Selective Late-Stage Functionalization of Unactivated C(sp3)-H Bonds”. Nat. Synth. 2022, 1, 794–803. [PDF Download], DOI: https://doi.org/10.1038/s44160-022-00125-1.

  • This paper was highlighted by Dr. Diane N. Le and Dr. Danielle M. Schultz in Nat. Synth.

  • This paper was featured by ScienceNet, 

  • This paper was featured by ChemStation.

 

54. Liu, C.#, Cui, X.#, Chen, W, Ma, X., Prather, K.J., Zhou, K.*, Wu, J.* "Synthesis of Oxygenated Sesquiterpenoids Enabled by Combining Metabolic Engineering and Visible-light Photocatalysis" Chem. Eur. J. 2022, 28, e202201230. [PDF Download] DOI: https://doi.org/10.1002/chem.202201230

53.Li, D., Liu, T., Hong, Y., Cao, C., Wu, J.* & Deng, H.*, "Stop-Flow Microtubing Reactor-Assisted Visible Light-Induced Hydrogen-Evolution Cross Coupling of Heteroarenes with C(sp3)–H Bonds." ACS Catal., 2022, 12, 4473–4480. [PDF Download​] DOI: 10.1021/acscatal.2c01087

Picture1.png
TOC.png
untitled.png
11.png
shixiangcheng.png
Picture1.png
bottom of page