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2025

99. Chi, W.; Wu, J.; Dong, Y.; Wu, J. & Zhu, Y. "Accelerated Exciton Dissociation and Charge Transfer via Third-Motif Engineered Conjugated Polymers for Photocatalytic Circulation-flow Synthesis of H2O2" Angew. Chem. Int. Ed., 2025. [PDF Download] DOI: https://doi.org/10.1002/anie.202508690

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98. Jiang, H.; Zhang, W.; Wu, J.; Wang, Q.; Wang, G.; O'Neill, P.; Dubbaka, S. & Wu, J. "Nickel-embedded three-in-one pyridyl-quinoline-linked covalent organic framework photocatalysts for universal C(sp2) cross-coupling reactions" Nat. Commun., 2025. [PDF Download] DOI: https://doi.org/10.1038/s41467-025-59541-4

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97. Shi, J.; Wang, G.; Tian, D.; Hai, X.; Meng, R.; Xu, Y.; Teng, Y.; Ma. L.; Xi. S.; Yang, Y.; Zhou, X.; Fu, X.; Li, H.; Cai, Q,; He, P.; Lin, H.; Chen, J.; Li, J.; Li, J.; He, Q.; Yang, Q.; Li, J.; Wu, D.; Wang, Y. G.; Wu, J. & Lu, J. "Defying the oxidative-addition prerequisite in cross-coupling through artful single-atom catalysts" Nat. Commun., 2025. [PDF Download] DOI: https://doi.org/10.1038/s41467-025-58579-8

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96. Liaw, W. M.; Hirata, H.; Zou, G.; Wu, J.; & Zhao, Y. (2025). "Borrowing Hydrogen/Chiral Enamine Relay Catalysis Enables Diastereo- and Enantioselective β‑C−H Functionalization of Alcohols" J. Am. Chem. Soc., 2025. [PDF Download] DOI: https://doi.org/10.1021/jacs.4c17355

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2024

95. Yang, Y.; Shi, J.; Liu, C.; Liu, Q.; Yang, J.; Tong, X.; Lu, J.; & Wu, J. (2024). "Engineered Polymeric Carbon Nitride for Photocatalytic Diverse Functionalization of Electronic-Rich Alkenes" Angew. Chem. Int. Ed., 2024. [PDF Download] DOI: https://doi.org/10.1002/anie.202417099

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94. Xin, X.; Geng, J.; Zhang, D.; Ang, H.; Wang, H.; Cheng, Y.; Liu, Y.; Toh, R.; Wu, J. & Wang, H. (2024). "Mechano-photoexcitation for organic synthesis using mechanoluminescent materials as photon sources" Nature Synthesis, 2024. [PDF Download] DOI: https://doi.org/10.1038/s44160-024-00681-8

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93. Tian, D.; Tan, T.; Toh, R.; Wang, G.; Mohamed, F.; Yu, Z.; Ang, H.; Xu, W.; Tan, Q.; Ng, P.; Low, C.; Liu, B.; Quek, P.; Joy, J.; Cherian, J.; Mak, F. & Wu, J. (2024). "Button-Push On-Demand Synthesis for Rapid Optimization of Antiviral Peptidomimetics" J. Am. Chem. Soc., 2024. [PDF Download] DOI: https://doi.org/10.1021/jacs.4c12834

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92. Zeng, H.; Yin, R.; Zhao, Y.; Ma, J. & Wu, J. (2024). "Modular alkene synthesis from carboxylic acids, alcohols and alkanes via integrated photocatalysis" Nat. Chem., 2024. [PDF Download] DOI: https://doi.org/10.1038/s41557-024-01642-6

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91. Qi, J.; Wang, C.; Wang, G.; O’Neill, P.; Dubbaka, S.; Ang, H.; Chen, X. & Wu, J. (2024). "Strain-Release-Driven Electrochemical Skeletal Rearrangement of Non-Biased Alkyl Cyclopropanes/butanes" Angew. Chem. Int. Ed., 2024. [PDF Download] DOI: https://doi.org/10.1002/anie.202413723

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90. Liu, T.; Li, T.; Tea, Z.; Wang C.; Shen, T.; Lei, Z.; Chen, X.; Zhang W.; & Wu, J. (2024). "Modular assembly of arenes, ethylene and heteroarenes for the synthesis of 1,2-arylheteroaryl ethanes" Nat. Chem., 2024. [PDF Download] DOI: https://doi.org/10.1038/s41557-024-01560-7

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89. Wu, M.; Wu, Z.; Ang, H.; Wang, B.; Liu, T.; Wu, S.; Lei, Z.; Liaw, M.; Chanmungkalakul, S.; Lee, C.; Liu, X.; Lu, Y.; Lu, Y. & Wu, J. (2024). "Enhanced Reactivity of Acridinium Perchlorate: Harnessing Redox Mediators for Trace Chloride Activation in Hydrogen Atom Transfer Photocatalysis" ACS Catalysis, 2024. [PDF Download] DOI: https://doi.org/10.1021/acscatal.4c01910

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88. Tong, X.; Wu, Z.; Ang, H.; Miao, Y.; Lu, Y. & Wu, J. (2024). "Photocatalytic Reductive Functionalization of Aryl Alkynes via Alkyne Radical Anions" ACS Catalysis, 2024. [PDF Download] DOI: https://doi.org/10.1021/acscatal.4c02638

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87. Ang, H.; Miao, Y.; Ravelli, D.; & Wu, J. (2024). "Pyridine N-oxides as hydrogen atom transfer reagents for site-selective photoinduced C(sp3)–H functionalization" Nature Synthesis, 2024. [PDF Download] DOI: https://doi.org/10.1038/s44160-024-00528-2

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86. Lei, Z.; & Wu, J. (2024). "Terminal-selective C(sp3)–H borylation of unbranched alkanes enabled by intermolecular radical sampling and LMCT photocatalysis" National Science Review, 2024. [PDF Download] DOI: https://doi.org/10.1093/nsr/nwae105

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85. Song, L.; Ang, H. T.; Senthilperumal, J.; Kanusu, U. R.; Venugopal, S.; Rangarajan, N.; Krishnamoorthy, S.; Dubbaka, S., R.; O'Neill. P. & Wu, J. (2024). "1,2,3-Triazole Synthesis: Development of Safe and Effective Batch and Continuous Manufacturing Processes" Org. Process Res. Dev., 2024. [PDF Download] DOI: https://doi-org.libproxy1.nus.edu.sg/10.1021/acs.oprd.4c00020

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84. Liu, C.; Song, L.; Liu, Q.; Chen, W.; Xu, J.; Wang, M.; Zhang, Y.; Tan, T., W.; Lei, Z.; Cheng, L.; Khan SA.; & Wu, J. (2024). "High-Speed Circulation Flow Platform Facilitating Practical Large-Scale Heterogeneous Photocatalysis." Org. Process Res. Dev., 2024. [PDF Download] DOI: https://doi-org.libproxy1.nus.edu.sg/10.1021/acs.oprd.

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83. Zhang, X.; Li, S.; Qiu, F.; Ang, H. T.; Wu, J. & Jia, P. (2024) "Photocatalyzed Minisci-type reactions for late-stage
functionalization of pharmaceutically relevant compounds" Green Chem., 2024. [PDF Download] DOI: https://doi.org/10.1039/D3GC05089K

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82. Wang, Q.; Yin, R.; Wang, Z.; Zhang, Y.; Wu, J. (2023) "Application of stop‑flow micro‑tubing reactor system in organic reaction development" Journal of Flow Chemistry, 2023. [PDF Download] DOI: https://doi.org/10.1007/s41981-023-00302-z

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2023

81. Qi, J.; Wang, X.; Wang, G.; Dubbaka, S.; O`Neil, P.; Ang, H.; Wu, J. (2023) "Sustainable electrocatalytic oxidation of N-alkylamides to acyclic imides using H2O" Green Chemistry, 2024. [PDF Download] DOI: https://doi.org/10.1039/D3GC04010K

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80. Lei, Z.; Zhang, W.; Wu, J. (2023) "Photocatalytic hydrogen atom transfer-induced Arbuzov-type α-C(sp3)-H phosphonylation of aliphatic amines" ACS Catalysis, 2023. [PDF Download] DOI: https://doi.org/10.1021/acscatal.3c04621

79. Qi, J.; Xu, J.; Ang, H. T.; Wang, B.; Gupta, N.; Dubbaka, S.; O'Neill, P.; Mao, X.; Lum, Y.; Wu, J. (2023) "Electrophotochemical Synthesis Facilitated Trifluoromethylation of Arenes Using Trifluoroacetic Acid" J. Am. Chem. Soc. 2023. [PDF Download​] DOI: https://doi.org/10.1021/jacs.3c10148

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78. Song, L.; Wu, J. (2023) "Modular synthesis of β-amino acids from alkenes, amines, and CO2 via photoredox/copper dual catalysis" Science China Chemsitry 2023. [PDF Download​] DOI: https://doi.org/10.1007/s11426-023-1848-9

77. Hai, X.; Zheng, Y.; Yu, Q.; Guo, N.; Xi, S.; Zhao, X.; Mitchell, S.; Luo, X.; Tulus, V.; Wang, M.; Sheng, X.; Ren, L.; Long, X.; Li, J.; He, P.; Lin, H.; Cui, Y.; Peng, X.; Shi, J.; Wu, J.; Zhang, C.; Zou, R.; Guillén-Gosálbez, G.; Pérez-Ramírez, J.; Koh, M. J.; Zhu, Y.; Li, J & Lu, J. (2023) "Geminal-atom Catalysis for Cross-coupling" Nature 2023. [PDF Download​] DOI: https://doi.org/10.1038/s41586-023-06529-z

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76. Zhang, Z., Wang, C., Li, L., Piper, J. L., Peng, Z., Ma, J., Zhang, F. & Wu, J. (2023) "Programmable Synthesis of Difluorinated Hydrocarbons from Alkenes through a Photocatalytic Linchpin Strategy" Chem. Sci. 2023, Accepted.

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75. Zhang, W., Liu, T., Ang, H. T., Luo, P., Lei, Z., Luo, X., Koh, M. J. & Wu, J. (2023) "Modular and Practical 1,2-Aryl(alkenyl) Heteroatom Functionalization of Alkenes through Iron/Photoredox Dual Catalysis" Angew. Chem. Int. Ed. 2023, e202310978. [PDF Download​] DOI: https://doi.org/10.1002/anie.202310978

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74. Xu, J., Xu, W., Zhang, X., Wu, J., Zhang, P., Song, L., & Liu, X. (2023) "Divergent Synthesis of Quinolones through Radical C–H Functionalization/Cyclization" Advanced Synthesis & Catalysis. [PDF Download​] DOI: https://doi.org/10.1002/adsc.202300426

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73. Yang, H.#, Xu, J.#, Cao, H., Wu, J.* & Zhao, Dan.*. (2023) "Recovery of Homogeneous Photocatalysts by Covalent Organic Framework Membranes" Nature Communications. 14, 2726. [PDF Download​] DOI: https://doi.org/10.1038/s41467-023-38424-6

  • This paper was featured by X-MOL, 

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72. Wang, G., Ang, H., T., & Wu, J.*. (2023). "Multi-Step Automated Synthesis of Pharmaceuticals" Trends in Chemistry. Accepted. [PDF Download] DOI: https://doi.org/10.1016/j.trechm.2023.03.008

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71. Zhu, K., Ma, Y., Wu, Z., Wu, J.* & Lu, Y.*. (2023). "Energy-Transfer-Enabled Regioconvergent Alkylation of Azlactones via Photocatalytic Radical–Radical Coupling" ACS Catalysis, 13, 4894–4902. [PDF Download​] DOI: https://doi.org/10.1021/acscatal.2c05698

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70. Kong, D.#, Zhang, M.#, Zhang, Y., Yu, Z., Cao, H.*, & Wu, J.*. (2023). "Photocatalyzed Regioselective Hydrosilylation for the Divergent Synthesis of Geminal and Vicinal Borosilanes." Nature Communications. 14, 2525. [PDF Download​] DOI: https://doi.org/10.1038/s41467-023-38224-y

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69. Lei, Z., Ang, H., T., & Wu, J.* (2023). "Advanced In-line Purification Technologies in Multistep Continuous Flow Pharmaceutical Synthesis." Organic Process Research & Development. Accepted. [PDF Download​] DOI: https://doi.org/10.1021/acs.oprd.2c00374

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68. Lim, Y.-J., Tang, G., Ye, Z., Zhang, C.-J. Wu, J.*, & Yao, S. Q.* (2023). "A Late-Stage Aryl C-H Olefination Strategy and Its Application Towards Global Proteome Profiling of ∆8-Tetrahydrocannabinol." Chemistry - A European Journal. e202300531. [PDF Download​] DOI: https://doi.org/10.1002/chem.202300531

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67. Ng, X. Q.#, Lim, C. S.#, Liaw, M. W., Quanch, T. T., Yang, B., Isoni, V., Wu, J.*, & Zhao, Y.* (2023). "Direct Access to Chiral Aliphatic Amines by Catalytic Enantioconvergent Redox-neutral Amination of Alcohols." 

Nature Synthesis. 2, 572–580. [PDF Download​] DOI: https://doi.org/10.1038/s44160-023-00264-z

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66. Yuan, Y.#, Zhang, M.#, Tang, X., Piper, J. L., Peng, Z. H., Ma, J. A.*, Wu, J.*, & Zhang, F. G.* (2023). "Photoinduced Defluorinative Branch-Selective Olefination of Multifluoro (Hetero) arenes." Organic Letters. 25, 883−888. [PDF Download​] DOI: https://doi.org/10.1021/acs.orglett.3c00115

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65. Fan, X.#, Zhang, M.#, Gao, Y., Zhou. Q., Zhang, Y., Yu, J., Xu, W., Yan, J., Liu, H., Lei, Z., Ter, Y. C., Chanmungkalakul, S., Lum, Y., Liu, X., Cui, G., & Wu, J.* (2023)."Stepwise On-demand Functionalization of Multihydrosilanes Enabled by a Hydrogen-atom-transfer Photocatalyst Based on Eosin Y." Nature Chemistry. 15, 666–676. [PDF Download​] DOI: https://doi.org/10.1038/s41557-023-01155-8

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64. Tang, H., Zhang, M.*, Zhang, Y., Luo, P., Ravelli, D.; Wu, J.* (2023)."Direct Synthesis of Thioesters from Feedstock Chemicals and Elemental Sulfur." Journal of the American Chemical Society. 145(10), 5846–5854. [PDF Download​] DOI: https://doi.org/10.1021/jacs.2c13157

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63. Wu, Z., Wu, M., Zhu, K., Wu, J.*, Lu, Y.* (2023)."Photocatalytic Coupling of Electron-deficient Alkenes using Oxalic Acid as a Traceless Linchpin." Chem. 9(4), 978-988. [PDF Download​] DOI: https://doi.org/10.1016/j.chempr.2022.12.013

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