39. Wang, H., Toh, R. W., Shi, X., Wang, T., Cong, X., Wu, J.* "Photo-mediated Selective Deconstructive Geminal Dihalogenation of Trisubstituted Alkenes" Nat. Commun., 2020, Accepted Paper. DOI: 10.1038/s41467-020-18274-2

38. Kuang, Y., Cao, H., Tang, H., Chew, J., Chen, W., Shi, X., Wu, J.* "Visible Light Driven Deuteration of Formyl C-H and Hydridic C(sp3)-H Bonds in Feedstock Chemicals and Pharmaceutical Molecules" Chemical Science, 2020, 11, 8912-8918. DOI: 1039/D0SC02661A 







37. Yan, J., Cheo, H. W., Teo, W. K., Shi, X., Wu, H., Idres, S. B., Deng, L. W., and Wu, J.*. "A Radical Smiles Rearrangement Promoted by Neutral Eosin Y as a Direct Hydrogen Atom Transfer Photocatalyst" Journal of the American Chemical Society, 2020, 142(26), 11357–11362. DOI: 10.1021/jacs.0c02052

36. Zhang, Y., Yang, X., Wu, J.*, and Huang, D.* "Aerobic C–H Functionalization Using Pyrenedione as the Photocatalyst" Synthesis2020, Accepted Paper (invited article from Synthesis) DOI: 10.1055/s-0040-1707135





35. Zheng, L., Xue, H.,Wong, W. K., Cao, H, Wu, J.* and Khan, A. S.*"Cloud-inspired multiple scattering for light
intensified photochemical flow reactors" Reaction Chemistry & Engineering, 2020, 5, 1058-1063. DOI: 10.1039/D0RE00080A










34. Jia, P., Li, Q., Poh, W. C., Jiang, H., Liu, H., Deng, H., and Wu, J.* "Light-Promoted Bromine Radical-Mediated Selective Alkylation and Amination of Unactivated C(sp3)-H Bonds." Chem, 2020, 6(7), 1766-1776. DOI: 10.1016/j.chempr.2020.04.022






33. Cao, H., Kuang, Y., Shi, X., Wong, K. L., Tan, B. B., Kwan, J. M. C., Liu, X., and Wu, J.* "Photoinduced site-selective alkenylation of alkanes and aldehydes with aryl alkenes." Nat. Commun., 2020, 11(1), 1956. DOI: 10.1038/s41467-020-15878-6


32. Xu, W., Jiang, H., Leng, J., Ong, H. and Wu, J.* "Visible‐Light‐Induced Selective Defluoroborylation of Polyfluoroarenes, gem‐Difluoroalkenes, and Trifluoromethylalkenes." Angew. Chem. Int. Ed., 2020, 59, 4009-4016. DOI: 10.1002/anie.201911819

31. Zhang, Y., Yang, X., Tang, H., Liang, D., Wu, J.*, and Huang, D.*, "Pyrenediones as Versatile Photocatalysts for Oxygenation Reactions with in situ Generation of Hydrogen Peroxide under Visible Light." Green Chem., 2020, 22, 22-27. DOI: 10.1039/C9GC03152A

30. Kuang, Y. , Wang, K. , Shi, X. , Huang, X. , Meggers, E. and Wu, J.* "Asymmetric Synthesis of 1,4‐Dicarbonyl Compounds from Aldehydes via the Marriage of Hydrogen Atom Transfer Photocatalysis with Chiral Lewis Acid Catalysis." Angew. Chem. Int. Ed.. 2019, 58, 16859-16863. DOI:10.1002/anie.201910414

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29. Liu, R., Chia, S. P. M., Goh, Y. Y., Cheo, H. W., Fan, B., Li, R., Zhou, R.*, Wu, J.* "Visible‐Light‐Mediated Regioselective Allylation, Benzylation, and Silylation of Methylene‐Malononitriles via Photoredox‐Induced Radical Cation Fragmentation" Eur. J. Org. Chem. 2020, 10, 1459-1465. DOI: 10.1002/ejoc.201900902.







28. Fan, X., Xiao, P., Jiao, Z., Yang, T., Dai, X., Xu, W., Tan, J. D., Cui, G.,* Su, H., Fang, W., Wu, J.* "Neutral-Eosin-Y-Photocatalyzed Silane Chlorination Using Dichloromethane" Angew. Chem. Int. Ed. 2019, 58, 12580-12584. DOI: 10.1002/anie.201908556.

  • This paper was highlighted by X-MOL.



27. Zhou, R., Li, J., Cheo, H. W., Chua, R., Zhan, G., Hou, Z., Wu, J.* "Visible-light-mediated Deuteration of Silanes with Deuterium Oxide" Chem. Sci. 201910, 7340–7344. DOI: 10.1039/C9SC02818H.






26. Xu, J.-H., Wu, W.-B., Wu, J.* "Photoinduced Divergent Alkylation/Acylation of Pyridine N-Oxides with Alkynes under Anaerobic and Aerobic Conditions" Org. Lett. 2019, 21, 5321–5325. DOI: 10.1021/acs.orglett.9b01940.

25. Ou, W., Zhang, G., Wu, J., Su, C.* "Photocatalytic Cascade Radical Cyclization Approach to Bioactive Indoline-Alkaloids over Donor–Acceptor Type Conjugated Microporous Polymer" ACS Catal. 2019, 9, 5178–5183. DOI: 10.1021/acscatal.9b00693.

24. Wong, Y. -C., Wu, W.-B., Wang, T., Ng, J. D. A., Khoo, K. H.,* Wu, J.*, Tan, Z.-K. "Color Patterning of Luminescent Perovskites via Light‐Mediated Halide Exchange with Haloalkanes" Adv. Mater. 2019, 1901247. DOI: 10.1002/adma.201901247.


23. "Young Career Focus: Dr. Jie Wu" Synform 2019, 05, A68–A70. DOI: 10.1055/s-0037-1612161.

22. Ng, C. K., Toh, R. W., Lin, T. T., Luo, H.-K., Hor, T. S. A.,* Wu, J.* "Metal-salen molecular cages as efficient and recyclable heterogeneous catalysts for cycloaddition of CO2 with epoxides at ambient conditions" Chem. Sci. 201910, 1549–1554. DOI: 10.1039/C8SC05019H.


  • This paper was highlighted by Synfacts 201915, 0540 (By Prof. Yasuhiro Uozumi, and Prof. Anggi Eka Putra).

21. Li, J., Luo Y., Cheo, H. W., Lan, Y.,* Wu, J.* "Photoredox Catalysis Modulated Nickel-Catalyzed Divergent Difunctionalization of Ethylene" Chem 2019, 5, 192–203. DOI: 10.1016/j.chempr.2018.10.006


20. Xue, C.-W., Li, J., Lee, J. P., Zhang, P.,* Wu, J.* "Continuous Amination of Aryl/Heteroaryl Halides Using Aqueous Ammonia in a Teflon AF-2400 Tube-in-Tube Micro-Flow Reactor" Reaction Chemistry & Engineering 20184, 346–350  (Invited article for special issue "RCE Emerging Investigators 2019"). DOI: 10.1039/C8RE00216A.





19. Cao, H., Jiang, H., Feng, H., Kwan, J. M. C., Liu, X., Wu, J.* "Photo-Induced Decarboxylative Heck-Type Coupling of Unactivated Aliphatic Acids and Terminal Alkenes in the Absence of Sacrificial Hydrogen Acceptors" J. Am. Chem. Soc. 2018, 47, 16360–16367. DOI: 10.1021/jacs.8b11218.

18. Hou, J., Ee, A., Cao, H., Ong, H.-W., Xu, J.-H. Wu, J.* "Visible‐Light‐Mediated Metal‐Free Difunctionalization of Alkenes with CO2 and Silanes or C(sp3)-H Alkanes" Angew. Chem. Int. Ed. 201857, 17220–17224. DOI: 10.1002/anie.201811266.



  • This paper has been selected as Hot Paper by Angewandte Chemie International Edition (Topics: C-H Activation
    , Carbon Dioxide, and Photocatalysis).

  • This paper was highlighted by Synfacts 2019, 15, 0198 (From Prof. Benjamin List).

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17. Deng, H.-P., Zhou, Q., Wu, J.* "Micro-Tubing Reactor-Assisted Aliphatic C-H Functionalization Utilizing HCl as the Hydrogen Atom Transfer Catalyst Precursor in Conjunction with an Organo Photoredox Catalyst" Angew. Chem. Int. Ed. 201857,12661–12665. DOI: 10.1002/anie.201804844.








16. Wu, W.-B., Wong, Y.-C., Tan, Z.-K.,* Wu, J.* "Photo-induced thiol coupling and C–H activation using nanocrystalline lead-halide perovskite catalysts" Catal. Sci. Technol. 20188, 4257–4263. DOI: 10.1039/c8cy01240g.


15. Li, J.-S., Wu, J.* "Recent Development of Photo-Mediated Generation of Silyl Radicals and Their Application in Organic Synthesis" ChemPhotoChem 2018, 2, 839–846. DOI: 10.1002/cptc.201800110 (Invited Review).

14. Liu, H., Ma, L., Zhou, R., Chen, X.,* Fang, W., Wu, J.* "One-Pot Photo-Mediated Giese Reaction/Friedel-Crafts Hydroxyalkylation/Oxidative Aromatization to Access Naphthalene Derivatives from Toluenes and Enones" ACS Catal. 20188, 6224–6229. DOI: 10.1021/acscatal.8b00481

  • This paper was highlighted by X-MOL.


13. Hou, J., Li, J.-S., Wu, J.* "Recent Development of Light-Mediated Carboxylation Using CO2 as the Feedstock" Asian J. Org. Chem. 2018, 7, 1439–1447. DOI: 10.1002/ajoc.201800226 (Invited Review).

  • Top 10% most downloaded papers of Asian J. Org. Chem in 2019.

12. Fan, X.-Z., Rong, J.-W., Wu, H.-L., Zhou, Q., Deng, H.-P., Tan, J. D., Xue, C.-W., Wu, L.-Z., Tao, H.-R., Wu, J.* 
"Eosin Y as a Direct Hydrogen Atom Transfer Photocatalyst for the Functionalization of C-H Bonds" Angew. Chem. Int. Ed. 2018, 57, 8514–8518. Manuscript. DOI: 10.1002/anie.201803220.






11. Hou, J., Ee, A., Feng, W., Xu, J.-H., Zhao, Y.,* Wu, J.* "Visible-Light-Driven Alkyne Hydro-/Carbocarboxylation Using CO2 via Iridium/Cobalt Dual Catalysis for Divergent Heterocycle Synthesis" J. Am. Chem. Soc. 2018, 140, 5257–5263. DOI: 10.1021/jacs.8b01561.

  • This work was highlighted by X-MOL.

10. Toh, R. W., Li, J. S., Wu, J. Utilization of Stop-flow Micro-tubing Reactors for the Development of Organic Transformations. J. Vis. Exp. 2018, (131), e56897, doi:10.3791/56897.


9. Zhou, R.; Goh, Y. Y.; Liu, H.; Tao, H.; Li, L.; Wu, J.* “Visible-Light-Mediated Metal-Free Hydrosilylation of Alkenes through Selective Hydrogen Atom Transfer for Si-H Activation” Angew. Chem. Int. Ed. 2017, 56(52), 16621–16625. DOI: 10.1002/anie.201711250.









8. Deng, H.; Fan, X.; Chen, Z.; Xu, Q.; & Wu, J.* "Photo-induced nickel-catalyzed chemo- and regioselective hydroalkylation of internal alkynes with ether and amide a-hetero C(sp3)-H bonds" J. Am. Chem. Soc. 2017, 139, 13579–13584. DOI: 10.1021/jacs.7b08158.








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7. Zhou, R.; Liu, H.; Tao, H.; Yu, X.; & Wu, J.* "Metal-free direct alkylation of unfunctionalized allylic/benzylic sp 3 C–H bonds via photoredox induced radical cation deprotonation." Chem. Sci. 2017, 8(6), 4654–4659., DOI: 10.1039/C7SC00953D.








6. Xue, F.; Deng, H.; Xue, C.; Mohamed, D. K. B.; Tang, K. Y.; Wu, J.* “Reaction Discovery Using Acetylene Gas as the Chemical Feedstock Accelerated by the ‘Stop-Flow’ Micro-Tubing Reactor System” Chem. Sci. 2017, 8(5), 3623–3627. DOI: 10.1039/C7SC00408G. (Co-first authors)









5. Wu, J.; Li, J.; Xue, C.; Mohamed D. “Lotus-Type Reactor for Large-Scale Continuous-Flow and Stop-Flow Synthesis” 2017, Patent application No. 10201700300X.


4. Wu, J.; Deng H.; Xue, F.; Mohamed, D. “Modular ‘Stop-Flow’ Parallel Microtubing Reactor Platform Useful for High-Pressure Reaction Screening” 2016, US 62/320726 (US Provisional Patent).

3. Cai, B., Evans, R. W., Wu, J., & Panek, J. S. Total Synthesis of Nuclear Factor of Activated T-Cells-68 (NFAT-68): Sequential Use of Chiral Allenylsilane and Titanium Alkoxide-Mediated Reductive Coupling Bond Construction. Org. Lett, 2016, 18(17), 4304–4307.

2. Ng, C. K.; Wu, J.*; Hor, T. S. A.*; Luo, H.-K.* “A Binary Catalyst System of a Cationic Ru-CNC Pincer Complex with an Alkali Metal Salt for Selective Hydroboration of Carbon Dioxide” Chem. Comm. 2016, 52, 11842-11845.

1. Mohamed, D. K. B.; Yu, X.-J.; Li, J.-S.; Wu, J.* "Reaction Screening in Continuous Flow Reactors" Tetrahedron Lett. 2016, 57, 39653977. (Invited Review)

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